5-Day Italy In-Depth Tour from Rome with Tuscany: Assisi, Siena, Florence, Venice - 5 Days

5-Day Italy In-Depth Tour from Rome with Tuscany: Assisi, Siena, Florence, Venice

Enjoy an Italian holiday on our 5 day Italy tour from Rome, a great opportunity to take in Tuscany, Bologna, Florence, Venice, and more.

5-Day Italy In-Depth Tour from Rome with Tuscany: Assisi / Siena / Florence / Venice

Highlights
• Explore the walled city of Assisi
• Visit Florence, the Cradle of the Renaissance
• Take a stroll through the elegant lanes of Bologna
• Visit Padua, a famous Catholic pilgrimage site
• Visit Montepulciano, Tuscany’s wine region

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Top attractions in Rome

St. Peter's Basilica

St. Peter’s Basilica

St. Peter's Basilica is largest and most important basilica in the Catholic world. Its spectacular interior is placed under the dome designed by Michelangelo. The construction of basilica started in...

Roman Forum

Roman Forum

Roman Forum (or Foro Romano in Italian) is large archaeological site in the heart of Rome, place with many well preserved remains of ancient structures, buildings and temples.

Rome, Colosseum

Colosseum

Known originally as the Flavian Amphitheatre, Colosseum is the most famous Roman landmark and it owes its name to the giant statue of the emperor Nero that once stood near...

More travel info about Rome and Italy

Rome, Colosseum

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Top hotels in Rome

Palazzo Naiadi, The Dedica Anthology

Palazzo Naiadi, The Dedica Anthology

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NH Collection Palazzo Cinquecento

NH Collection Palazzo Cinquecento

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Roma Luxus Hotel

Roma Luxus Hotel

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Grand Hotel De La Minerve

Grand Hotel De La Minerve

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Singer Palace Hotel

Singer Palace Hotel

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Cheap flights and hotels discounts for Rome

Day 1
Rome – Assisi – Siena – Florence

Get ready for a wonderful 5-day tour of Italy to experience Italy’s wealthy culture, architecture and cuisine!

In the early morning we will pick you up from Rome in our deluxe coach and start our voyage to Assisi’s walled city. This historic town, built in the Middle Ages, is packed with ancient wonders and unparalleled architecture. We’re going to have free lunch time (own cost) and exploring here. We strongly suggest visiting the St. Francis basilica, home to Giotto and Cimabue masterpieces.

Next, we head north to Siena, one of Italy’s most famous towns and a UNESCO World Heritage Site. From here we will arrive at Florence’s amazing town.

Day 2
Florence

Enjoy this morning a scrumptious breakfast before we start our Renaissance Cradle exploration-and trust us, you’ll need it. Today we’re going to dig deep into the wealthy culture, wonderful sites, and intriguing history of Florence.

Also known as the Middle Ages Athens, Florence quickly extended as Europe’s free trade centre. This prosperity permitted Renaissance patrons and artists to thrive. In the enchanting landmarks and architecture, like the iconic Duomo, you can see proof of this prosperity.

Our tour will take us to the Campanile Tower and the Baptistery from this popular attraction, home to the amazing bronze gates where Michelangelo envisioned the Paradise Gates. Next, we’re going to move to the core of the town where we’ll find Piazza della Signoria, Palazzo della Signoria (also known as Palazzo Vecchio) and Santa Croce Basilica.

After a dinner at a local Tuscan restaurant in Piazza Santa Croce, you will be free to explore Florence’s cobblestone streets on your own. Or join us on an optional trip to Pisa (own cost) to see the UNESCO-listed Miracle Square, including Pisa’s Leaning Tower.

Day 3
Florence – Bologna – Padua – Venice

We’re going to have a final breakfast in Florence today before we say goodbye to this immaculate city and travel to Bologna.

You will have the chance to explore Bolgna’s elegant streets and squares. We will walk through the core of the town from Piazza Malpighi to Piazza del Nettuno and Piazza Maggiore. From here our walking tour will take us past the Palace of King Renzo, Palazzo Podesta, and one of the largest of its kind in the world, the Basilica of San Petronio.

We’ll be back on the highway by the evening, traveling to Padua. Here we will visit one of the most visited pilgrimage locations in the Catholic world, the world-famous Sant’Antonio Basilica.

By midday we will arrive in Venice, one of the most romantic towns in the world and without a doubt the most lovely man-made town!

Day 4
Venice

Enjoy a private water-taxi transfer to Piazza San Marco after breakfast at the hotel, with tickets for Skip the Line to the beautiful St. Mark’s Basilica. Then check out the Floating City’s most famous areas: the Doge’s Palace, a symbol of the glorious past of Venice; as well as the legendary Sighs Bridge. Spend the evening roaming at your leisure along the storied canals of Venice, then go back to the hotel for lunch and rest for a nice night.

Day 5
Venice - Montepulciano - Rome

We will leave Venice after breakfast and head to Tuscany, famous for its landscapes, lovely churches and castles, and delicious wines. We will find our way to Val di Chiana with a stop in Montepulciano, a medieval town wealthy in art and history, also known for its Nobile wine, which can be purchased in local wine houses. Spend the evening exploring Montepulciano at your own speed, enjoying free wine tastings, or maybe shopping. We’ll go back to Rome in the evening, where the trip service finishes.